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Psoriatic arthritis patients face higher risk of heart disease, says study

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New research shows that the risk of cardiovascular disease is higher in patients with psoriatic arthritis.

The study led by the Mayo Clinic in Rochester, Minnesota, examined the cardiovascular disease risk profile of 158 patients newly diagnosed with psoriatic arthritis.

Researchers then compared the observed incidence of cardiovascular events with that predicted by the Framingham Risk Score (FRS), a commonly-used tool for estimating the 10-year cardiovascular risk of an individual.

When first diagnosed with psoriatic arthritis, 34% of the patients had two or more cardiovascular risk factors.

Among the 126 patients aged 30 years or older at disease onset with no prior history of heart disease, 33% had an FRS rating of 10% or higher, and 11% had an FRS of 20% or above. In the ten years after diagnosis with psoriatic arthritis, 18 experienced a cardiovascular event.

The researchers said that the ten-year cumulative incidence of cardiovascular events was 17% in this patient group. That´s almost twice as high as the predicted incidence based on the FRS.

Reporting their findings in the journal Arthritis Care & Research, the authors of the study concluded: “The majority of newly diagnosed psoriatic arthritis patients have a greater than 10 per cent risk of cardiovascular disease within ten years of psoriatic arthritis incidence. The cardiovascular disease risk in these patients is higher than expected and underestimated by the FRS.”

A spokeswoman for the charity Arthritis Research UK, commenting on the study, said: “People with psoriasis and psoriatic arthritis may also have a slightly greater risk of developing heart disease, so it´s important to tackle anything that could add to this risk, such as smoking, drinking a lot of alcohol, being overweight and blood pressure problems.”

http://www.arthritisresearchuk.org/news/general-news/2015/july/cardiovascular-disease-risk-higher-in-psoriatic-arthritis-patients.aspx

http://www.doctorslounge.com/index.php/news/pb/56450

http://onlinelibrary.wiley.com/doi/10.1002/acr.22536/abstract